Research Progress in Molecular Mechanism of Broad-spectrum Disease Resistance in Rice

Yield loss caused by crop diseases seriously restricts global food security. Breeding disease-resistant varieties with resistant（R） gene is acknowledged as the most economical and effective way to control diseases. Therefore, exploring broad-spectrum resistant（BSR） genes to pathogens and clarifying the underlying mechanism are the basis for effective utilization of BSR resources and finding the new approaches for disease control. In the past 20 years, significant progress has also been made in plant immune mechanism and remarkable achievements have been made in researches on broad-spectrum disease resistance of major grain crops, and the potential molecular mechanisms of some BSR have been revealed. Here, the advances of broad-spectrum disease resistance in rice（including the representative cloned BSR genes and their molecular mechanisms） were reviewed. In addition, the problems, opportunities and challenges encountered by BSR were analyzed, and the development of BSR research and its application in rice production were prospected.